Increased waist circumference is the optimal predictor of incident metabolic syndrome - 04/2005

Predictors of the incident metabolic syndrome in adults: the Insulin Resistance Atherosclerosis Study.- 2005

139 of the 714 white, black, and Hispanic participants in the Insulin Resistance Atherosclerosis Study (IRAS) who were free of the metabolic syndrome at baseline developed the metabolic syndrome in the subsequent 5 years. After adjustment for age, sex, study site, ethnicity, and impaired glucose tolerance, the best predictors of incident metabolic syndrome were waist circumference (>89 cm in women, >102 cm in men; odds ratio [OR] 1.7 [1.3-2.0] per 11 cm), followed by HDL cholesterol (0.6 [0.4-0.7] per 15 mg/dl) and proinsulin (1.7 [1.4-2.0] per 3.3 pmol/l). Waist circumference was the optimal predictor.

Themes : Metabolic Syndrome and Epidemiology

Author(s) :
Palaniappan L, Carnethon MR, Wang Y, Hanley AJ, Fortmann SP, Haffner SM, Wagenknecht L; Insulin Resistance Atherosclerosis Study

Reference :
Diabetes Care 2004;27(3):788-93.

Pubmed reference :
PMID: 14988303