Impaired fasting glucose is highly prevalent in Chinese children and adolescents with prehypertension/hypertension

A total of 3409 children and adolescents were enrolled in this study aimed to assess the prevalence of impaired fasting glucose among Chinese children with prehypertension/hypertension (PHP/HP), overweight/obesity (OW/OB) or both. The subjects were divided into four groups: OW/OB, PHP/HP, OW/OB + PHP/HP, and a control group. Fasting plasma glucose (FPG) and lipid levels were measured in children with a body mass index ≥85th percentile or a blood pressure ≥90th percentile, as well as in 100 subjects randomly-selected from the control group. Data analysis revealed that the prevalence of impaired fasting glucose in PHP/HP did not significantly differ from that found in OW/OB + PHP/HP, but was higher than that in the OW/OB group. In conclusion, children and adolescents with PHP/HP exhibit a higher prevalence of impaired fasting glucose than those with OW/OB. Further validation of these findings is warranted, and a screening protocol for hyperglycaemia in Chinese children and adolescents should be considered for implementation.

Abstract

Keywords:
High blood pressure – Hypertension – IFG – Obesity – OGTT – Overweight – Plasma glucose